Package: CITMIC Type: Package Title: Estimation of Cell Infiltration Based on Cell Crosstalk Version: 0.1.1 Maintainer: Junwei Han Authors@R: c(person(given = "Junwei", family = "Han", email = "hanjunwei1981@163.com", role = c("aut", "cre", "cph")), person(given = "Xilong", family = "Zhao", role = "aut") ) Description: A systematic biology tool was developed to identify cell infiltration via an Individualized Cell crosstalk network. 'CITMIC' first constructed a weighted cell crosstalk network by integrating Cell-target interaction information, biological process data from the Gene Ontology (GO) database, and gene transcriptomic data in a specific sample, and then, it used a network propagation algorithm on the network to identify cell infiltration for the sample. Ultimately, cell infiltration in the patient dataset was obtained by normalizing the centrality scores of the cells. License: GPL (>= 2) Encoding: UTF-8 LazyData: true Depends: R (>= 2.10) Imports: fastmatch, igraph, parallel, stats RoxygenNote: 7.2.3 Suggests: knitr, rmarkdown VignetteBuilder: knitr Config/pak/sysreqs: libglpk-dev libxml2-dev Repository: https://hanjunwei-lab.r-universe.dev Date/Publication: 2024-09-26 06:53:30 UTC RemoteUrl: https://github.com/hanjunwei-lab/citmic RemoteRef: HEAD RemoteSha: fc6ea713d92d876d1cc10c97307736a6c7c628bb NeedsCompilation: no Packaged: 2026-06-23 08:07:18 UTC; root Author: Junwei Han [aut, cre, cph], Xilong Zhao [aut]