Package: DrugSim2DR
Type: Package
Title: Predict Drug Functional Similarity to Drug Repurposing
Version: 0.1.1
Maintainer: Junwei Han <hanjunwei1981@163.com>
Authors@R: c(person(given = "Junwei", family = "Han", email = "hanjunwei1981@163.com", role  = c("aut", "cre", "cph")),
             person(given = "Ji", family = "Li", role  = "aut"),
             person(given = "Jiashuo", family = "Wu", role  = "aut"))
Description: A systematic biology tool was developed to repurpose drugs
        via a drug-drug functional similarity network. 'DrugSim2DR'
        first predict drug-drug functional similarity in the context of
        specific disease, and then using the similarity constructed a
        weighted drug similarity network. Finally, it used a network
        propagation algorithm on the network to identify drugs with
        significant target abnormalities as candidate drugs.
License: GPL (>= 2)
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.2.1
Imports: igraph, stats, pheatmap, ChemmineR, rvest, base, sp, tidyr,
        reshape2, fastmatch
Suggests: knitr, rmarkdown
VignetteBuilder: knitr
Depends: R (>= 3.6)
Config/pak/sysreqs: cmake libglpk-dev make libicu-dev libpng-dev
        librsvg2-dev libuv1-dev libxml2-dev libssl-dev
Repository: https://hanjunwei-lab.r-universe.dev
Date/Publication: 2025-06-09 11:22:17 UTC
RemoteUrl: https://github.com/hanjunwei-lab/drugsim2dr
RemoteRef: HEAD
RemoteSha: 697888f5bb7962f07f294c4f4452354e4dc5713c
NeedsCompilation: no
Packaged: 2026-07-04 05:56:51 UTC; root
Author: Junwei Han [aut, cre, cph],
  Ji Li [aut],
  Jiashuo Wu [aut]