Package: MiRSEA
Type: Package
Version: 1.1
Date: 2015-06-30
Title: 'MicroRNA' Set Enrichment Analysis
Author: Junwei Han, Siyao Liu
Maintainer: Junwei Han <hanjunwei1981@163.com>
Description: The tools for 'MicroRNA Set Enrichment Analysis' can
        identify risk pathways(or prior gene sets) regulated by
        microRNA set in the context of microRNA expression data. (1)
        This package constructs a correlation profile of microRNA and
        pathways by the hypergeometric statistic test. The gene sets of
        pathways derived from the three public databases (Kyoto
        Encyclopedia of Genes and Genomes ('KEGG'); 'Reactome';
        'Biocarta') and the target gene sets of microRNA are provided
        by four databases('TarBaseV6.0'; 'mir2Disease'; 'miRecords';
        'miRTarBase';). (2) This package can quantify the change of
        correlation between microRNA for each pathway(or prior gene
        set) based on a microRNA expression data with cases and
        controls. (3) This package uses the weighted Kolmogorov-Smirnov
        statistic to calculate an enrichment score (ES) of a microRNA
        set that co-regulate to a pathway , which reflects the degree
        to which a given pathway is associated with the specific
        phenotype. (4) This package can provide the visualization of
        the results.
Collate: Corrp2miRfile.R EnrichmentScore.R S2N.R MirSEA.R MsReport.R
        GetExampleData.R getEnvironmentData.R GetMiRTargetData.R
        GetPathwayData.R PlotCorrelation.R PlotHeatMap.R
        PlotRunEnrichment.R
LazyData: Yes
Depends: R (>= 2.15.1)
Suggests: stats,graphics,grDevices
License: GPL (>= 2)
biocViews: Statistics, Pathways, microRNA, enrichment analysis
Packaged: 2026-06-07 07:26:48 UTC; root
NeedsCompilation: no
Repository: https://hanjunwei-lab.r-universe.dev
Date/Publication: 2020-06-30 13:18:48 UTC
RemoteUrl: https://github.com/hanjunwei-lab/mirsea
RemoteRef: HEAD
RemoteSha: 2914d2e41ba742589d80e91c0559cc3e83e3692b