Package: SubtypeDrug
Type: Package
Title: Prioritization of Candidate Cancer Subtype Specific Drugs
Version: 0.1.6
Author: Xudong Han, Junwei Han, Chonghui Liu
Maintainer: Junwei Han <hanjunwei1981@163.com>
Description: A systematic biology tool was developed to prioritize
        cancer subtype-specific drugs by integrating genetic
        perturbation, drug action, biological pathway, and cancer
        subtype. The capabilities of this tool include inferring
        patient-specific subpathway activity profiles in the context of
        gene expression profiles with subtype labels, calculating
        differentially expressed subpathways based on cultured human
        cells treated with drugs in the 'cMap' (connectivity map)
        database, prioritizing cancer subtype specific drugs according
        to drug-disease reverse association score based on subpathway,
        and visualization of results (Castelo (2013)
        <doi:10.1186/1471-2105-14-7>; Han et al (2019)
        <doi:10.1093/bioinformatics/btz894>; Lamb and Justin (2006)
        <doi:10.1126/science.1132939>). Please cite using
        <doi:10.1093/bioinformatics/btab011>.
License: GPL (>= 2)
Depends: R (>= 2.10)
Encoding: UTF-8
LazyData: true
BugReports: https://github.com/hanjunwei-lab/SubtypeDrug/issues
RoxygenNote: 7.2.3
Imports:
        BiocGenerics,GSVA,grDevices,graphics,igraph,parallel,pheatmap,rvest,stats,xml2,ChemmineR
Suggests: knitr, rmarkdown, testthat (>= 3.0.0)
VignetteBuilder: knitr
NeedsCompilation: no
Packaged: 2026-07-04 08:36:28 UTC; root
Config/testthat/edition: 3
Config/pak/sysreqs: cmake libglpk-dev make libmagick++-dev gsfonts
        libicu-dev libpng-dev librsvg2-dev libuv1-dev libxml2-dev
        libssl-dev zlib1g-dev
Repository: https://hanjunwei-lab.r-universe.dev
Date/Publication: 2024-01-11 12:11:05 UTC
RemoteUrl: https://github.com/hanjunwei-lab/subtypedrug
RemoteRef: HEAD
RemoteSha: 4bd48f9b196732a30439641a49de2d6a9b70f7e0