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  "Title": "Identification of Dysregulated MiRNAs Based on MiRNA-MiRNA\nInteraction Network",
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  "Description": "A systematic biology tool was developed to identify\ndysregulated miRNAs via a miRNA-miRNA interaction network.\n'IDMIR' first constructed a weighted miRNA interaction network\nthrough integrating miRNA-target interaction information,\nmolecular function data from Gene Ontology (GO) database and\ngene transcriptomic data in specific-disease context, and then,\nit used a network propagation algorithm on the network to\nidentify significantly dysregulated miRNAs.",
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      "title": "IDMIR User Guide",
      "author": "Xilong Zhao, Jiashuo Wu, Junwei Han",
      "engine": "knitr::rmarkdown",
      "headings": [
        "Introduce",
        "<font face=\"微软雅黑\">Example 1 : Calculate the GDEscore. </font>",
        "<font face=\"微软雅黑\"> Example 2 : Identify candidate miRNAs by random-walk algorithm. </font>",
        "<font face=\"微软雅黑\"> Example 3 : Build a multivariate Cox regression model using the targets of a single miRNA.</font>",
        "<font face=\"微软雅黑\"> Example 4 : Build a multivariate Cox regression model by integrating the models constructed separately based on different miRNA targets.</font>",
        "<font face=\"微软雅黑\"> Visualize 1: Plot the Kaplan-Meier curve. </font>",
        "<font face=\"微软雅黑\"> Visualize 2: Plot the heatmap of miRNA targets expression.</font>",
        "",
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        "<font face=\"微软雅黑\"> Visualize 4: Plot the Scatter diagram.</font>"
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      "modified": "2023-11-09 16:36:06",
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