{
  "_id": "6a251e6b4b233be19838f923",
  "Package": "MiRSEA",
  "Type": "Package",
  "Version": "1.1",
  "Date": "2015-06-30",
  "Title": "'MicroRNA' Set Enrichment Analysis",
  "Author": "Junwei Han, Siyao Liu",
  "Maintainer": "Junwei Han <hanjunwei1981@163.com>",
  "Description": "The tools for 'MicroRNA Set Enrichment Analysis' can\nidentify risk pathways(or prior gene sets) regulated by\nmicroRNA set in the context of microRNA expression data. (1)\nThis package constructs a correlation profile of microRNA and\npathways by the hypergeometric statistic test. The gene sets of\npathways derived from the three public databases (Kyoto\nEncyclopedia of Genes and Genomes ('KEGG'); 'Reactome';\n'Biocarta') and the target gene sets of microRNA are provided\nby four databases('TarBaseV6.0'; 'mir2Disease'; 'miRecords';\n'miRTarBase';). (2) This package can quantify the change of\ncorrelation between microRNA for each pathway(or prior gene\nset) based on a microRNA expression data with cases and\ncontrols. (3) This package uses the weighted Kolmogorov-Smirnov\nstatistic to calculate an enrichment score (ES) of a microRNA\nset that co-regulate to a pathway , which reflects the degree\nto which a given pathway is associated with the specific\nphenotype. (4) This package can provide the visualization of\nthe results.",
  "Collate": "Corrp2miRfile.R EnrichmentScore.R S2N.R MirSEA.R MsReport.R\nGetExampleData.R getEnvironmentData.R GetMiRTargetData.R\nGetPathwayData.R PlotCorrelation.R PlotHeatMap.R\nPlotRunEnrichment.R",
  "LazyData": "Yes",
  "License": "GPL (>= 2)",
  "biocViews": "Statistics, Pathways, microRNA, enrichment analysis",
  "Packaged": {
    "Date": "2026-06-07 07:26:48 UTC",
    "User": "root"
  },
  "NeedsCompilation": "no",
  "Repository": "https://hanjunwei-lab.r-universe.dev",
  "Date/Publication": "2020-06-30 13:18:48 UTC",
  "RemoteUrl": "https://github.com/hanjunwei-lab/mirsea",
  "RemoteRef": "HEAD",
  "RemoteSha": "2914d2e41ba742589d80e91c0559cc3e83e3692b",
  "MD5sum": "f345119b8b46c3bbfe79383a33a2cf67",
  "_user": "hanjunwei-lab",
  "_type": "src",
  "_file": "MiRSEA_1.1.tar.gz",
  "_fileid": "dd2960641dd54e939c48eff3b70172970208d1bd9ab01fdcaa04e07b73ce5546",
  "_filesize": 1283822,
  "_sha256": "dd2960641dd54e939c48eff3b70172970208d1bd9ab01fdcaa04e07b73ce5546",
  "_created": "2026-06-07T07:26:48.000Z",
  "_published": "2026-06-07T07:31:55.504Z",
  "_distro": "noble",
  "_jobs": [
    {
      "job": 79940782404,
      "time": 93,
      "config": "linux-devel-x86_64",
      "r": "4.7.0",
      "check": "NOTE",
      "artifact": "7461885743"
    },
    {
      "job": 79940782401,
      "time": 98,
      "config": "linux-release-x86_64",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7461886819"
    },
    {
      "job": 79940782398,
      "time": 87,
      "config": "macos-oldrel-arm64",
      "r": "4.5.3",
      "check": "NOTE",
      "artifact": "7461892800"
    },
    {
      "job": 79940782408,
      "time": 73,
      "config": "macos-release-arm64",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7461913572"
    },
    {
      "job": 79940604621,
      "time": 179,
      "config": "source",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7461872357"
    },
    {
      "job": 79940782391,
      "time": 96,
      "config": "wasm-release",
      "r": "4.6.0",
      "check": "OK",
      "artifact": "7461886251"
    },
    {
      "job": 79940782395,
      "time": 70,
      "config": "windows-devel",
      "r": "4.7.0",
      "check": "NOTE",
      "artifact": "7461882615"
    },
    {
      "job": 79940782403,
      "time": 71,
      "config": "windows-oldrel",
      "r": "4.5.3",
      "check": "NOTE",
      "artifact": "7461882729"
    },
    {
      "job": 79940782407,
      "time": 75,
      "config": "windows-release",
      "r": "4.6.0",
      "check": "NOTE",
      "artifact": "7461883306"
    }
  ],
  "_buildurl": "https://github.com/r-universe/hanjunwei-lab/actions/runs/27086037125",
  "_status": "success",
  "_host": "GitHub-Actions",
  "_upstream": "https://github.com/hanjunwei-lab/mirsea",
  "_commit": {
    "id": "2914d2e41ba742589d80e91c0559cc3e83e3692b",
    "author": "hanjunwei-lab <hanjunwei1981@163.com>",
    "committer": "hanjunwei-lab <hanjunwei1981@163.com>",
    "message": "update readme\n",
    "time": 1593523128
  },
  "_maintainer": {
    "name": "Junwei Han",
    "email": "hanjunwei1981@163.com",
    "login": "hanjunwei-lab",
    "description": "Junwei Han is a professor in Harbin Medical University. His research is in the areas of bioinformatics and computational systems biology.",
    "uuid": 60877533
  },
  "_registered": true,
  "_dependencies": [
    {
      "package": "R",
      "version": ">= 2.15.1",
      "role": "Depends"
    },
    {
      "package": "stats",
      "role": "Suggests"
    },
    {
      "package": "graphics",
      "role": "Suggests"
    },
    {
      "package": "grDevices",
      "role": "Suggests"
    }
  ],
  "_owner": "hanjunwei-lab",
  "_selfowned": true,
  "_usedby": 0,
  "_updates": [],
  "_tags": [],
  "_topics": [
    "statistics",
    "pathways",
    "microrna",
    "enrichment analysis"
  ],
  "_stars": 0,
  "_contributors": [
    {
      "user": "hanjunwei-lab",
      "count": 4,
      "uuid": 60877533
    }
  ],
  "_userbio": {
    "uuid": 60877533,
    "type": "user",
    "name": "Junwei Han",
    "description": "Junwei Han is a professor in Harbin Medical University. His research is in the areas of bioinformatics and computational systems biology."
  },
  "_downloads": {
    "count": 176,
    "source": "https://cranlogs.r-pkg.org/downloads/total/last-month/MiRSEA"
  },
  "_devurl": "https://github.com/hanjunwei-lab/mirsea",
  "_searchresults": 19,
  "_rbuild": "4.6.0",
  "_assets": [
    "extra/citation.cff",
    "extra/citation.html",
    "extra/citation.json",
    "extra/citation.txt",
    "extra/contents.json",
    "extra/MiRSEA.html",
    "extra/readme.html",
    "extra/readme.md",
    "manual.pdf"
  ],
  "_homeurl": "https://github.com/hanjunwei-lab/mirsea",
  "_realowner": "hanjunwei-lab",
  "_cranurl": true,
  "_releases": [
    {
      "version": "1.0",
      "date": "2015-05-31"
    },
    {
      "version": "1.1",
      "date": "2015-07-01"
    },
    {
      "version": "1.1.1",
      "date": "2024-01-24"
    }
  ],
  "_exports": [
    "Corrp2miRfile",
    "EnrichmentScore",
    "EnrichmentScore2",
    "Getenvir",
    "GetExampleData",
    "GetMiRTargetData",
    "GetPathwayData",
    "HeatMapPlot",
    "initializeMiRSEA",
    "MirSEA",
    "MsReport",
    "PlotCorrelation",
    "PlotHeatMap",
    "PlotRunEnrichment",
    "S2N"
  ],
  "_datasets": [
    {
      "name": "envData",
      "title": "The variables in the environment include predefine pathway, target information of miRNAs,an expression profile and a example result of miRNA list",
      "object": "envData",
      "class": [
        "environment"
      ],
      "fields": [],
      "table": false,
      "tojson": false
    }
  ],
  "_help": [
    {
      "page": "MiRSEA-package",
      "title": "MicroRNA Set Enrichment Analysis",
      "topics": [
        "MiRSEA-package",
        "MiRSEA"
      ]
    },
    {
      "page": "Corrp2miRfile",
      "title": "create a pathway-microRNA(miRNA) profile and a p value matrix",
      "topics": [
        "Corrp2miRfile"
      ]
    },
    {
      "page": "EnrichmentScore",
      "title": "Computes the enrichment score",
      "topics": [
        "EnrichmentScore"
      ]
    },
    {
      "page": "EnrichmentScore2",
      "title": "Computes the enrichment score faster",
      "topics": [
        "EnrichmentScore2"
      ]
    },
    {
      "page": "envData",
      "title": "The variables in the environment include predefine pathway, target information of miRNAs,an expression profile and a example result of miRNA list",
      "topics": [
        "envData",
        "example.cls",
        "example.gct",
        "mfile",
        "miRList",
        "p",
        "p2miR",
        "pathway"
      ]
    },
    {
      "page": "GetExampleData",
      "title": "Get the example data",
      "topics": [
        "GetExampleData"
      ]
    },
    {
      "page": "GetMiRTargetData",
      "title": "Get the data of microRNA(miRNA) and target genes",
      "topics": [
        "GetMiRTargetData"
      ]
    },
    {
      "page": "GetPathwayData",
      "title": "Get the gene sets of pathways",
      "topics": [
        "GetPathwayData"
      ]
    },
    {
      "page": "HeatMapPlot",
      "title": "Plot a heatmap",
      "topics": [
        "HeatMapPlot"
      ]
    },
    {
      "page": "MirSEA",
      "title": "Identify dysregulated pathways based on microRNA (miRNA) set enrichment analysis",
      "topics": [
        "MirSEA"
      ]
    },
    {
      "page": "MsReport",
      "title": "Produce report for a microRNA (abbreviated miRNA) set",
      "topics": [
        "MsReport"
      ]
    },
    {
      "page": "PlotCorrelation",
      "title": "Plot global microRNA(miRNA) correlation profile",
      "topics": [
        "PlotCorrelation"
      ]
    },
    {
      "page": "PlotHeatMap",
      "title": "Plot a heat map",
      "topics": [
        "PlotHeatMap"
      ]
    },
    {
      "page": "PlotRunEnrichment",
      "title": "Plot running microRNAs(miRNAs) enrichment score",
      "topics": [
        "PlotRunEnrichment"
      ]
    },
    {
      "page": "S2N",
      "title": "calculate signal to noise ratio for microRNAs(miRNAs)",
      "topics": [
        "S2N"
      ]
    }
  ],
  "_readme": "https://github.com/hanjunwei-lab/mirsea/raw/HEAD/README.md",
  "_rundeps": [],
  "_vignettes": [
    {
      "source": "MiRSEA.Rnw",
      "filename": "MiRSEA.pdf",
      "title": "MiRSEA Overview",
      "engine": "utils::Sweave",
      "headings": [],
      "created": "2020-06-27 10:38:03",
      "modified": "2020-06-27 10:38:03",
      "commits": 1
    }
  ],
  "_score": 3.9777236052888476,
  "_indexed": true,
  "_nocasepkg": "mirsea",
  "_universes": [
    "hanjunwei-lab"
  ],
  "_binaries": [
    {
      "r": "4.7.0",
      "os": "linux",
      "version": "1.1",
      "date": "2026-06-07T07:28:27.000Z",
      "distro": "noble",
      "commit": "2914d2e41ba742589d80e91c0559cc3e83e3692b",
      "fileid": "65df64bbe00bd57fe4688b7fbed0b23ad81aae2e9ae0c7f6dc5886d7c2361958",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/hanjunwei-lab/actions/runs/27086037125"
    },
    {
      "r": "4.6.0",
      "os": "linux",
      "version": "1.1",
      "date": "2026-06-07T07:28:32.000Z",
      "distro": "noble",
      "commit": "2914d2e41ba742589d80e91c0559cc3e83e3692b",
      "fileid": "eb4ae0d9f19309e6b003a6c5db732b22d6257048d4c330ab5c0a56f079aa139d",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/hanjunwei-lab/actions/runs/27086037125"
    },
    {
      "r": "4.5.3",
      "os": "mac",
      "version": "1.1",
      "date": "2026-06-07T07:29:12.000Z",
      "commit": "2914d2e41ba742589d80e91c0559cc3e83e3692b",
      "fileid": "90799bde4b0345ceb216d30e68f482c5e679234503b305bdf645efd79985f1c7",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/hanjunwei-lab/actions/runs/27086037125"
    },
    {
      "r": "4.6.0",
      "os": "mac",
      "version": "1.1",
      "date": "2026-06-07T07:31:33.000Z",
      "commit": "2914d2e41ba742589d80e91c0559cc3e83e3692b",
      "fileid": "6516fd9dbea20118fdde5689713b9cac26af076c7546880d10676599f15f6447",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/hanjunwei-lab/actions/runs/27086037125"
    },
    {
      "r": "4.6.0",
      "os": "wasm",
      "version": "1.1",
      "date": "2026-06-07T07:28:39.000Z",
      "commit": "2914d2e41ba742589d80e91c0559cc3e83e3692b",
      "fileid": "d9bbad2e86a4968e8e13981b8b501032a873b6ce08ad82fc9f6a32a9488ec170",
      "status": "success",
      "buildurl": "https://github.com/r-universe/hanjunwei-lab/actions/runs/27086037125"
    },
    {
      "r": "4.7.0",
      "os": "win",
      "version": "1.1",
      "date": "2026-06-07T07:27:59.000Z",
      "commit": "2914d2e41ba742589d80e91c0559cc3e83e3692b",
      "fileid": "d235103ad09f1e5da35eed78c3dee0d11ea9c7a60417340a1fc79a7914f4e5d1",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/hanjunwei-lab/actions/runs/27086037125"
    },
    {
      "r": "4.5.3",
      "os": "win",
      "version": "1.1",
      "date": "2026-06-07T07:27:57.000Z",
      "commit": "2914d2e41ba742589d80e91c0559cc3e83e3692b",
      "fileid": "aaf07cbd2f702d3907d358f0868023580e6167e3da60a65ac476c46f2549a87d",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/hanjunwei-lab/actions/runs/27086037125"
    },
    {
      "r": "4.6.0",
      "os": "win",
      "version": "1.1",
      "date": "2026-06-07T07:28:04.000Z",
      "commit": "2914d2e41ba742589d80e91c0559cc3e83e3692b",
      "fileid": "e6874718861c55337a1d187f54a3d03f79e8766743d68a39d8b0b23e191eaef2",
      "status": "success",
      "check": "NOTE",
      "buildurl": "https://github.com/r-universe/hanjunwei-lab/actions/runs/27086037125"
    }
  ]
}