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  "Description": "Immunotherapy has revolutionized cancer treatment, but\npredicting patient response remains challenging. Here, we\npresented Intelligent Predicting Response to cancer\nImmunotherapy through Systematic Modeling (iPRISM), a novel\nnetwork-based model that integrates multiple data types to\npredict immunotherapy outcomes. It incorporates gene\nexpression, biological functional network, tumor\nmicroenvironment characteristics, immune-related pathways, and\nclinical data to provide a comprehensive view of factors\ninfluencing immunotherapy efficacy. By identifying key genetic\nand immunological factors, it provides an insight for more\npersonalized treatment strategies and combination therapies to\novercome resistance mechanisms.",
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