Introduce | Example 1 : Calculate the DEscore. | Example 2 : Calculate drug-drug functional similarity. | Example 3 : Identify candidate drugs by random-walk algorithm. | Visualize 1: Plot the chemical structure of a compound. | Visualize 2: Plot the heatmap of drug targets expression. | Visualize 3: Plot a drug/GO bipartite network.
Package: DrugSim2DR 0.1.1
DrugSim2DR: Predict Drug Functional Similarity to Drug Repurposing
A systematic biology tool was developed to repurpose drugs via a drug-drug functional similarity network. 'DrugSim2DR' first predict drug-drug functional similarity in the context of specific disease, and then using the similarity constructed a weighted drug similarity network. Finally, it used a network propagation algorithm on the network to identify drugs with significant target abnormalities as candidate drugs.
Authors:
DrugSim2DR_0.1.1.tar.gz
DrugSim2DR_0.1.1.zip(r-4.7)DrugSim2DR_0.1.1.zip(r-4.6)DrugSim2DR_0.1.1.zip(r-4.5)
DrugSim2DR_0.1.1.tgz(r-4.6-any)DrugSim2DR_0.1.1.tgz(r-4.5-any)
DrugSim2DR_0.1.1.tar.gz(r-4.7-any)DrugSim2DR_0.1.1.tar.gz(r-4.6-any)
DrugSim2DR_0.1.1.tgz(r-4.6-emscripten)
manual.pdf |manual.html✨
DESCRIPTION
card.svg |card.png
DrugSim2DR/json (API)
| # Install 'DrugSim2DR' in R: |
| install.packages('DrugSim2DR', repos = c('https://hanjunwei-lab.r-universe.dev', 'https://cloud.r-project.org')) |
Bug tracker:https://github.com/hanjunwei-lab/drugsim2dr/issues
Datasets:
- myenv - An environment variable which includes some example data
Last updated from:697888f5bb. Checks:7 WARNING, 2 OK. Indexed: yes.
| Target | Result | Time | Files | Syslog |
|---|---|---|---|---|
| linux-devel-x86_64 | WARNING | 182 | ||
| source / vignettes | OK | 211 | ||
| linux-release-x86_64 | WARNING | 190 | ||
| macos-release-arm64 | WARNING | 111 | ||
| macos-oldrel-arm64 | WARNING | 105 | ||
| windows-devel | WARNING | 134 | ||
| windows-release | WARNING | 144 | ||
| windows-oldrel | WARNING | 123 | ||
| wasm-release | OK | 176 |
Exports:CalDEscoreDrugRepositionDrugSimscoreGettestplotDruglinkplotDrugstructureplotTargetheatmap
Dependencies:askpassbase64encBHBiocGenericsbitopsbslibcachemChemmineRclicpp11crosstalkcurlDBIdigestdplyrDTevaluatefarverfastmapfastmatchfontawesomefsgenericsggplot2gluegridExtragtablehighrhtmltoolshtmlwidgetshttrigraphisobandjquerylibjsonliteknitrlabelinglaterlatticelazyevallifecyclemagrittrMatrixmemoisemimeopensslotelpheatmappillarpkgconfigplyrpngpromisespurrrR6rappdirsRColorBrewerRcppRCurlreshape2rjsonrlangrmarkdownrsvgrvestS7sassscalesselectrspstringistringrsystibbletidyrtidyselecttinytexutf8vctrsviridisLitewithrxfunxml2yaml
Readme and manuals
Help Manual
| Help page | Topics |
|---|---|
| CalDEscore | CalDEscore |
| datasummary: Custom Data Summaries | DrugSim2DR-package DrugSim2DR |
| DrugReposition | DrugReposition |
| DrugSimscore | DrugSimscore |
| Gettest | Gettest |
| An environment variable which includes some example data | myenv |
| plotDruglink | plotDruglink |
| plotDrugstructure | plotDrugstructure |
| plotTargetheatmap | plotTargetheatmap |
