Package: DrugSim2DR 0.1.1

DrugSim2DR: Predict Drug Functional Similarity to Drug Repurposing

A systematic biology tool was developed to repurpose drugs via a drug-drug functional similarity network. 'DrugSim2DR' first predict drug-drug functional similarity in the context of specific disease, and then using the similarity constructed a weighted drug similarity network. Finally, it used a network propagation algorithm on the network to identify drugs with significant target abnormalities as candidate drugs.

Authors:Junwei Han [aut, cre, cph], Ji Li [aut], Jiashuo Wu [aut]

DrugSim2DR_0.1.1.tar.gz
DrugSim2DR_0.1.1.zip(r-4.5)DrugSim2DR_0.1.1.zip(r-4.4)DrugSim2DR_0.1.1.zip(r-4.3)
DrugSim2DR_0.1.1.tgz(r-4.5-any)DrugSim2DR_0.1.1.tgz(r-4.4-any)DrugSim2DR_0.1.1.tgz(r-4.3-any)
DrugSim2DR_0.1.1.tar.gz(r-4.5-noble)DrugSim2DR_0.1.1.tar.gz(r-4.4-noble)
DrugSim2DR_0.1.1.tgz(r-4.4-emscripten)DrugSim2DR_0.1.1.tgz(r-4.3-emscripten)
DrugSim2DR.pdf |DrugSim2DR.html✨
DrugSim2DR/json (API)

# Install 'DrugSim2DR' in R:
install.packages('DrugSim2DR', repos = c('https://hanjunwei-lab.r-universe.dev', 'https://cloud.r-project.org'))

Bug tracker:https://github.com/hanjunwei-lab/drugsim2dr/issues

Datasets:
  • myenv - An environment variable which includes some example data

On CRAN:

Conda:

4.00 score 2 stars 2 scripts 183 downloads 7 exports 89 dependencies

Last updated 2 years agofrom:cd15b9a56f. Checks:1 OK, 8 WARNING. Indexed: yes.

TargetResultLatest binary
Doc / VignettesOKMar 26 2025
R-4.5-winWARNINGMar 26 2025
R-4.5-macWARNINGMar 26 2025
R-4.5-linuxWARNINGMar 26 2025
R-4.4-winWARNINGMar 26 2025
R-4.4-macWARNINGMar 26 2025
R-4.4-linuxWARNINGMar 26 2025
R-4.3-winWARNINGMar 26 2025
R-4.3-macWARNINGMar 26 2025

Exports:CalDEscoreDrugRepositionDrugSimscoreGettestplotDruglinkplotDrugstructureplotTargetheatmap

Dependencies:askpassbase64encBHBiocGenericsbitopsbslibcachemChemmineRclicolorspacecpp11crosstalkcurlDBIdigestdplyrDTevaluatefansifarverfastmapfastmatchfontawesomefsgenericsggplot2gluegridExtragtablehighrhtmltoolshtmlwidgetshttpuvhttrigraphisobandjquerylibjsonliteknitrlabelinglaterlatticelazyevallifecyclemagrittrMASSMatrixmemoisemgcvmimemunsellnlmeopensslpheatmappillarpkgconfigplyrpngpromisespurrrR6rappdirsRColorBrewerRcppRCurlreshape2rjsonrlangrmarkdownrsvgrvestsassscalesselectrspstringistringrsystibbletidyrtidyselecttinytexutf8vctrsviridisLitewithrxfunxml2yaml

DrugSim2DR User Guide

Ji Li, Jiashuo Wu, JunweiHan

Rendered fromDrugSim2DR.Rmdusingknitr::rmarkdownon Mar 26 2025.

Last update: 2023-08-02
Started: 2023-08-02